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This type of ‘big data’ research will generate lots of statistical associations, some of which will be spurious

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Since semaglutide is a “pure” agonist of the GLP-1 receptor, it exclusively stimulates the phenomena controlled by this receptor, while the ability of tirzepatide to act simultaneously on the GLP-1 and GIP receptors enables the activation of all the processes mediated by these incretins (Figure 3)